37 Pubblicazioni su riviste scientifiche internazionali recensite su PubMed
8 Pubblicazioni su riviste nazionali, capitolo di libro
100+ atti di Congressi Internazionali e Nazionali (non riportati)


1. Luongo C, Martin C, Vella K, Marsili A, Ambrosio R, Dentice M, Harney JW, Salvatore D, Zavacki AM, Larsen PR. The selective loss of the type 2 iodothyronine deiodinase in mouse thyrotrophs increases basal TSH but blunts the thyrotropin response to hypothyroidism. 2015 Feb;156(2):745-54.

2. Dentice M, Ambrosio R, Damiano V, Sibilio A, Luongo C, Guardiola O, Yennek S, Zordan P, Minchiotti G, Colao A, Marsili A, Brunelli S, Del Vecchio L, Larsen PR, Tajbakhsh S, Salvatore D. Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression. Cell Metab. 2014 Dec 2;20(6):1038-48.

3. Giannaccini G, Betti L, Palego L, Marsili A, Santini F, Pelosini C, Fabbrini L, Schmid L, Giusti L, Maffei M, Lanza M, Cristofaro M, Baroni S, Mauri M, Vitti P, Fierabracci P, Lucacchini A. The expression of platelet serotonin transporter (SERT) in human obesity. BMC Neurosci. 2013 Oct 18;14(1):128.

4. Pelosini C, Maffei M, Ceccarini G, Marchi M, Marsili A, Galli G, Scartabelli G, Tamberi A, Latrofa F, Fierabracci P, Vitti P, Pinchera A, Santini F. Frequencyof the GPR7 Tyr135Phe allelic variant in lean and obese subjects. J Endocrinol Invest. 2013 Oct;36(9):712-5.

5. Aguayo-Mazzucato C, Zavacki AM, Marinelarena A, Hollister-Lock J, El Khattabi I, Marsili A, Weir GC, Sharma A, Larsen PR, Bonner-Weir S. Thyroid hormone promotes postnatal rat pancreatic beta cell development and glucoseresponsive insulin secretion through MAFA. Diabetes. 2013 May;62(5):1569-80.

6. Dentice M, Marsili A, Zavacki A, Larsen PR, Salvatore D. The deiodinases and the control of intracellular thyroid hormone signaling during cellular differentiation. Biochim Biophys Acta. 2013 Jul;1830(7):3937-45.

7. Zhu B, Shrivastava A, Luongo C, Chen T, Harney JW, Marsili A, Tran TV,Bhadouria A, Mopala R, Steen AI, Larsen PR, Zavacki AM. Catalysis leads to posttranslational inactivation of the type 1 deiodinase and alters its conformation. J Endocrinol. 2012 Jul;214(1):87-94.

8. Zhang Y, Li Y, Niepel MW, Kawano Y, Han S, Liu S, Marsili A, Larsen PR, Lee CH, Cohen DE. Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance. Proc Natl Acad Sci U S A. 2012, 3;109(14):5417-22.

9. Patwari P, Emilsson V, Schadt EE, Chutkow WA, Lee S, Marsili A, Zhang Y, Dobrin R, Cohen DE, Larsen PR, Zavacki AM, Fong LG, Young SG, Lee RT. The arrestin domain-containing 3 protein regulates body mass and energy expenditure. Cell Metab. 2011 Nov 2;14(5):671-83.

10. Marsili A, Sanchez E, Singru P, Harney JW, Zavacki AM, Lechan RM, Larsen PR. Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase. J Endocrinol. 2011 Oct;211(1):73-8.

11. Marsili A, Tang D, Harney JW, Singh P, Zavacki AM, Dentice M, Salvatore D, Larsen PR. Type II iodothyronine deiodinase provides intracellular 3,5,3′-triiodothyronine to normal and regenerating mouse skeletal muscle. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E818-24.

12. Marsili A, Aguayo-Mazzucato C, Chen T, Kumar A, Chung M, Lunsford EP, Harney JW, Van-Tran T, Gianetti E, Ramadan W, Chou C, Bonner-Weir S, Larsen PR, Silva JE, Zavacki AM. Mice with a targeted deletion of the type 2 deiodinase are insulin resistant and susceptible to diet induced obesity. PLoS One. 2011;6(6):e20832.

13. Ramadan W, Marsili A, Larsen PR, Zavacki AM, Silva JE. Type-2 iodothyronine 5’deiodinase (D2) in skeletal muscle of C57Bl/6 mice. II. Evidence for a role of D2 in the hypermetabolism of thyroid hormone receptor alpha-deficient mice. Endocrinology. 2011 Aug;152(8):3093-102.

14. Ramadan W, Marsili A, Huang S, Larsen PR, Silva JE. Type-2 iodothyronine 5’deiodinase in skeletal muscle of C57BL/6 mice. I. Identity, subcellular localization, and characterization. Endocrinology. 2011 Aug;152(8):3082-92.

15. Marsili A, Zavacki AM, Harney JW, Larsen PR. Physiological role and regulation of iodothyronine deiodinases: a 2011 update. J Endocrinol Invest. 2011 May;34(5):395-407.

16. Dentice M, Marsili A, Ambrosio R, Guardiola O, Sibilio A, Paik JH, Minchiotti G, DePinho RA, Fenzi G, Larsen PR, Salvatore D. The FoxO3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration. J Clin Invest. 2010 Nov 1;120(11):4021-30.

17. Marsili A, Ramadan W, Harney JW, Mulcahey M, Castroneves LA, Goemann IM, Wajner SM, Huang SA, Zavacki AM, Maia AL, Dentice M, Salvatore D, Silva JE, Larsen PR. Type 2 iodothyronine deiodinase levels are higher in slow-twitch than fast-twitch mouse skeletal muscle and are increased in hypothyroidism. Endocrinology. 2010 Dec;151(12):5952-60.

18. Kádár A, Sánchez E, Wittmann G, Singru PS, Füzesi T, Marsili A, Larsen PR, Liposits Z, Lechan RM, Fekete C. Distribution of hypophysiotropic thyrotropin-releasing hormone (TRH)-synthesizing neurons in the hypothalamic paraventricular nucleus of the mouse. J Comp Neurol. 2010 Oct 1;518(19):3948-61.

19. Eisenberg MC, Santini F, Marsili A, Pinchera A, DiStefano JJ 3rd. TSH regulation dynamics in central and extreme primary hypothyroidism. Thyroid. 2010 Nov;20(11):1215-28.

20. Santini F, Galli G, Maffei M, Fierabracci P, Pelosini C, Marsili A, Giannetti M, Castagna MG, Checchi S, Molinaro E, Piaggi P, Pacini F, Elisei R, Vitti P,Pinchera A. Acute exogenous TSH administration stimulates leptin secretion in vivo. Eur J Endocrinol. 2010 Jul;163(1):63-7.

21. Giannaccini G, Betti L, Palego L, Schmid L, Fabbrini L, Pelosini C, Gargini C,Da Valle Y, Lanza M, Marsili A, Maffei M, Santini F, Vitti P, Pinchera A,Lucacchini A. Human serotonin transporter expression during megakaryocytic differentiation of MEG-01 cells. Neurochem Res. 2010 Apr;35(4):628-35.

22. Santini F, Mantovani A, Cristaudo A, Rago T, Marsili A, Buselli R, Mignani A, Ceccarini G, Bastillo R, Taddei D, Ricco I, Vitti P, Pinchera A. Thyroid function and exposure to styrene. Thyroid. 2008 Oct;18(10):1065-9.

23. Di Bello V, Santini F, Di Cori A, Pucci A, Talini E, Palagi C, Delle Donne MG, Marsili A, Fierabracci P, Valeriano R, Scartabelli G, Giannetti M, Anselmino M, Pinchera A, Mariani M. Effects of bariatric surgery on early myocardial alterations in adult severely obese subjects. Cardiology. 2008;109(4):241-8.

24. Giannaccini G, Giusti L, Santini F, Marsili A, Betti L, Mascia G, Pelosini C, Baroni S, Ciregia F, Fabbrini L, Lucacchini A, Vitti P, Pinchera A. Tubby protein in human lymphocytes from normal weight and obese subjects. Clin Biochem. 2007 Jul;40(11):806-9.

25. Santini F, Giannetti M, Mazzeo S, Fierabracci P, Scartabelli G, Marsili A, Valeriano R, Pucci A, Anselmino M, Zampa V, Vitti P, Pinchera A. Ultrasonographic evaluation of liver volume and the metabolic syndrome in obese women. J Endocrinol Invest. 2007 Feb;30(2):104-10.

26. Di Bello V, Santini F, Di Cori A, Pucci A, Palagi C, Delle Donne MG, Fierabracci P, Marsili A, Talini E, Giannetti M, Biadi O, Balbarini A, Mariani M, Pinchera A. Obesity cardiomyopathy: is it a reality? An ultrasonic tissue characterization study. J Am Soc Echocardiogr. 2006 Aug;19(8):1063-71.

27. Castagna MG, Pinchera A, Marsili A, Giannetti M, Molinaro E, Fierabracci P, Grasso L, Pacini F, Santini F, Elisei R. Influence of human body composition on serum peak thyrotropin (TSH) after recombinant human TSH administration in patients with differentiated thyroid carcinoma. J Clin Endocrinol Metab. 2005 Jul;90(7):4047-50.

28. Santini F, Pinchera A, Marsili A, Ceccarini G, Castagna MG, Valeriano R, Giannetti M, Taddei D, Centoni R, Scartabelli G, Rago T, Mammoli C, Elisei R,Vitti P. Lean body mass is a major determinant of levothyroxine dosage in thetreatment of thyroid diseases. J Clin Endocrinol Metab. 2005 Jan;90(1):124-7.

29. Chiellini C, Santini F, Marsili A, Berti P, Bertacca A, Pelosini C, Scartabelli G, Pardini E, López-Soriano J, Centoni R, Ciccarone AM, Benzi L, Vitti P, Del Prato S, Pinchera A, Maffei M. Serum haptoglobin: a novel marker of adiposity in humans. J Clin Endocrinol Metab. 2004 Jun;89(6):2678-83.

30. Santini F, Marsili A, Mammoli C, Valeriano R, Scartabelli G, Pelosini C, Giannetti M, Centoni R, Vitti P, Pinchera A. Serum concentrations of adiponectin and leptin in patients with thyroid dysfunctions. J Endocrinol Invest. 2004 Feb;27(2):RC5-7.

31. Santini F, Maffei M, Ceccarini G, Pelosini C, Scartabelli G, Rosellini V, Chiellini C, Marsili A, Lisi S, Tonacchera M, Agretti P, Chiovato L, Mammoli C, Vitti P, Pinchera A. Genetic screening for melanocortin-4 receptor mutations in a cohort of Italian obese patients: description and functional characterization of a novel mutation. J Clin Endocrinol Metab. 2004 Feb;89(2):904-8.

32. Santini F, Vitti P, Ceccarini G, Mammoli C, Rosellini V, Pelosini C, Marsili A, Tonacchera M, Agretti P, Santoni T, Chiovato L, Pinchera A. In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity. J Endocrinol Invest. 2003 Oct;26(10):950-5.

33. Luisella Vigna, Laura Tomaino, Veronica Lotito, Maria Rosaria Ingenito, Alessandra Piontini and Alessandro Marsili. Cyclic VLCKD Meal Replacement in a Patient with Obesity and Mild Chronic Kidney Disease following Kidney Transplantation. Obesities 2022, 2, 342–349.

34. Donatella Marazziti , Laura Betti , Stefano Baroni, Lionella Palego, Federico Mucci, Barbara Carpita, IvanMirco Cremone , Ferruccio Santini, Laura Fabbrini, Caterina Pelosini, Alessandro Marsili, Enrico Massimetti, Gino Giannaccini, Liliana Dell’Osso. The complex interactions among serotonin, insulin, leptin, and glycolipid metabolic parameters in human obesity CNS Spectr 2022 Feb;27(1):99-108.

35. Luisella Vigna, Laura Tomaino, Veronica Lo Tito, Francesco Di Pierro, Maria Rosaria Ingenito, Daniela Sommaruga, Alessandra Piontini, Alessandro Marsili. Killing Three Birds with One Stone: VLCKD In a Female Patient with Obesity, Celiac Disease and Migraine Progress in Nutrition 2021; Vol. 23, N. 4: e2021331.

36. Carmody C, Ogawa-Wong AN, Martin C, Luongo C, Zuidwijk M, Sager B, Petersen T, Roginski Guetter A, Janssen R, Wu EY, Bogaards S, Neumann NM, Hau K, Marsili A, Boelen A, Silva JE, Dentice M, Salvatore D, Wagers AJ, Larsen PR, Simonides WS, Zavacki AM A Global Loss of Dio2 Leads to Unexpected Changes in Function and Fiber Types of Slow Skeletal Muscle in Male Mice. Endocrinology. 2019 May 1;160(5):1205-1222.

37. Iodine nutritional status and thyroid effects of exposure to ethylenebisdithiocarbamates. Medda E, Santini F, De Angelis S, Franzellin F, Fiumalbi C, Perico A, Gilardi E, Mechi MT, Marsili A, Citroni A, Leandri A, Mantovani A, Vitti P, Olivieri A. Environ Res. 2017 Apr;154:152-159.


  1. Santini, A. Marsili, A. Pinchera, Alimentazione e Obesita’: le implicazioni sulla salute individuale e della collettività e relative strategie d’intervento. In: Alimentazione-la sfida del nuovo millennio. A cura di albero Michelini, Fabula in Art, L’Erma di Bretschneider, 2012 (con il Patrocinio del Ministero delle Politiche Agricole, Alimentari e Forestali). ISBN: 978-88-8265-733-8.
  2. Zavacki AM, Marsili A, and Larsen PR. Control of Thyroid Hormone Activation and Inactivation by the Iodothyronine Deiodinase Family of Selenoenzymes. In “Selenium” by Dolph L. Hatfield, Marla J. Berry & Vadim N. Gladyshev Springer Science+Business Media, LLC, ISBN: 978-1-4614-1024-9.
  3. Santini F, Marsili A, Pinchera A. Obesità e tiroide. In : Bosello O. “Obesità-Un trattato Multidisciplinare” II Edizione Editrice Kurtis, Milano 2009. ISBN: 978-88-85030-64-0.
  4. Santini F, Marsili A, Pinchera A. Obesità e funzione tiroidea. In : Pinchera A. “Obesità e sistema endocrino” Mediserve SrL, Milano, 2006, pag 87-97. ISBN 88-8204-146-8.
  5. Santini F., Brunetti M., Lippi C., Jaccheri R., Scartabelli G., Valeriano R., Valenti F., Macchi E., Griesi E, Verdiani C., Marsili A., Giannetti M., Ceccarini G., Biddau M., Lemmi F., Canu C., Virgone E., Baracchini G., Pinchera A. Indagine epidemiologica sulla prevalenza del sovrappeso e dell’obesita’ nella popolazione scolare pisana. Toscana Medica. 2004 Apr; 9-12.
  6. Santini F., Marsili A., Pinchera A. Insulino-resistenza ed obesità: basi genetiche comuni. In: Del Prato S. (Ed.), Lo studio genetico ed il modello animale verso la comprensione del legame tra obesità ed insulino-resistenza. Primula Multimedia S.r.L., Pisa, 2003, pp. 11-24. ISBN 88-87344-64-7.
  7. Santini F., Marsili A., Pinchera A. Metformina e obesità. In: Marchetti P (Ed.), Metformina: i successi di oggi, le sfide di domani. Pacini Editore SpA, Pisa, 2002, pp. 43-53. ISBN 88-7781-462-4.
  8. Santini F, Giannetti M, Valeriano R, Marsili A, Scartabelli G, Lippi C, Jaccheri R, Biddau M, Pinchera A. Epidemiologia dell’obesità. In: Anselmino M, Solito B, Bellini R, Rossi M. Bendaggio gastrico svedese regolabile per via laparoscopica. [CD-ROM]. Padova-Surgical Video Production, 2006